Detalhe da pesquisa
1.
Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization.
Immunity
; 49(2): 288-300.e8, 2018 08 21.
Artigo
Inglês
| MEDLINE | ID: mdl-30097292
2.
A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
PLoS Pathog
; 18(3): e1010409, 2022 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35344575
3.
Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex.
J Biol Chem
; 297(4): 101102, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34419446
4.
Structure and mechanism of monoclonal antibody binding to the junctional epitope of Plasmodium falciparum circumsporozoite protein.
PLoS Pathog
; 16(3): e1008373, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32150583
5.
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
PLoS Pathog
; 16(8): e1008753, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32866207
6.
Modeling of Hidden Structures Using Sparse Chemical Shift Data from NMR Relaxation Dispersion.
Biophys J
; 120(2): 296-305, 2021 01 19.
Artigo
Inglês
| MEDLINE | ID: mdl-33301748
7.
Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein.
Proc Natl Acad Sci U S A
; 114(48): E10438-E10445, 2017 11 28.
Artigo
Inglês
| MEDLINE | ID: mdl-29138320
8.
A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine.
PLoS Pathog
; 13(10): e1006682, 2017 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-29059230
9.
Slow Dynamics of Tryptophan-Water Networks in Proteins.
J Am Chem Soc
; 140(2): 675-682, 2018 01 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29256600
10.
Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion.
J Am Chem Soc
; 139(32): 11233-11240, 2017 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-28737940
11.
Multi-probe relaxation dispersion measurements increase sensitivity to protein dynamics.
Phys Chem Chem Phys
; 18(8): 5789-98, 2016 Feb 17.
Artigo
Inglês
| MEDLINE | ID: mdl-26426424
12.
Cofactor-Mediated Conformational Dynamics Promote Product Release From Escherichia coli Dihydrofolate Reductase via an Allosteric Pathway.
J Am Chem Soc
; 137(29): 9459-68, 2015 Jul 29.
Artigo
Inglês
| MEDLINE | ID: mdl-26147643
13.
Inhibition of ligand exchange kinetics via active-site trapping with an antibody fragment.
Biochemistry
; 53(12): 1879-81, 2014 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24617671
14.
Mechanistic analysis of allosteric and non-allosteric effects arising from nanobody binding to two epitopes of the dihydrofolate reductase of Escherichia coli.
Biochim Biophys Acta
; 1834(10): 2147-57, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23911607
15.
An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity that Reverses Carfentanil-Induced Respiratory Depression.
bioRxiv
; 2023 Jul 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37461607
16.
An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
ACS Chem Neurosci
; 14(16): 2849-2856, 2023 08 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37534714
17.
Affinity-matured homotypic interactions induce spectrum of PfCSP structures that influence protection from malaria infection.
Nat Commun
; 14(1): 4546, 2023 07 28.
Artigo
Inglês
| MEDLINE | ID: mdl-37507365
18.
Structural and biophysical correlation of anti-NANP antibodies with in vivo protection against P. falciparum.
Nat Commun
; 12(1): 1063, 2021 02 16.
Artigo
Inglês
| MEDLINE | ID: mdl-33594061
19.
Functional human IgA targets a conserved site on malaria sporozoites.
Sci Transl Med
; 13(599)2021 06 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34162751
20.
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity.
J Exp Med
; 217(11)2020 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-32790871